Calasept® EDTA Irrigation agent for root canal walls chelating and smear layer removal Calasept EDTA is specially formulated to aid in the negotiation of root canals by endodontic instruments. The EDTA forms a water soluble chelate complex that decalcifies substances and dissolves smear layers, thereby increasing the adhesion of filling material. EDTA helps to enlarge and shape the canal for final obturation. For maximum effect, flush intermittently with EDTA and sodium hypochlorite. Irrigation Agent Rinse the root canal thoroughly after use of EDTA. Calasept CHX is recommended for final rinsing.